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ARF stimulates XPC to trigger nucleotide excision repair by regulating the repressor complex of E2F4
The tumour suppressor ARF (alternative reading frame), which is mutated or silenced in various tumours, has a crucial role in tumour surveillance to suppress unwarranted cell growth and proliferation. ARF has also been linked to the DNA-damage-induced response of p53 because of its ability to inhibi...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2750060/ https://ncbi.nlm.nih.gov/pubmed/19644500 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2009.139 |
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