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Twist-open mechanism of DNA damage recognition by the Rad4/XPC nucleotide excision repair complex

DNA damage repair starts with the recognition of damaged sites from predominantly normal DNA. In eukaryotes, diverse DNA lesions from environmental sources are recognized by the xeroderma pigmentosum C (XPC) nucleotide excision repair complex. Studies of Rad4 (radiation-sensitive 4; yeast XPC orthol...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Velmurugu, Yogambigai, Chen, Xuejing, Slogoff Sevilla, Phillip, Min, Jung-Hyun, Ansari, Anjum
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4843471/
https://ncbi.nlm.nih.gov/pubmed/27035942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1514666113
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