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Twist-open mechanism of DNA damage recognition by the Rad4/XPC nucleotide excision repair complex

DNA damage repair starts with the recognition of damaged sites from predominantly normal DNA. In eukaryotes, diverse DNA lesions from environmental sources are recognized by the xeroderma pigmentosum C (XPC) nucleotide excision repair complex. Studies of Rad4 (radiation-sensitive 4; yeast XPC orthol...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Velmurugu, Yogambigai, Chen, Xuejing, Slogoff Sevilla, Phillip, Min, Jung-Hyun, Ansari, Anjum
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2016
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4843471/
https://ncbi.nlm.nih.gov/pubmed/27035942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1514666113
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