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Twist-open mechanism of DNA damage recognition by the Rad4/XPC nucleotide excision repair complex

DNA damage repair starts with the recognition of damaged sites from predominantly normal DNA. In eukaryotes, diverse DNA lesions from environmental sources are recognized by the xeroderma pigmentosum C (XPC) nucleotide excision repair complex. Studies of Rad4 (radiation-sensitive 4; yeast XPC orthol...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Velmurugu, Yogambigai, Chen, Xuejing, Slogoff Sevilla, Phillip, Min, Jung-Hyun, Ansari, Anjum
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4843471/
https://ncbi.nlm.nih.gov/pubmed/27035942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1514666113
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