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Identification of β-catenin as a target of the intracellular tyrosine kinase PTK6
Disruption of the gene encoding protein tyrosine kinase 6 (PTK6) leads to increased growth, impaired enterocyte differentiation and higher levels of nuclear β-catenin in the mouse small intestine. Here, we demonstrate that PTK6 associates with nuclear and cytoplasmic β-catenin and inhibits β-catenin...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Company of Biologists
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2954247/ https://ncbi.nlm.nih.gov/pubmed/20026641 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.053264 |
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