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Induction of Protein Tyrosine Kinase 6 in Mouse Intestinal Crypt Epithelial Cells Promotes DNA-Damage Induced Apoptosis

BACKGROUND & AIMS: Protein tyrosine kinase 6 (PTK6) is expressed in epithelial linings of the gastrointestinal tract. PTK6 sensitizes the non-transformed Rat1a fibroblast cell line to apoptotic stimuli. The aim of this study was to determine if PTK6 regulates apoptosis in vivo after DNA damage i...

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Detalhes bibliográficos
Main Authors: Haegebarth, Andrea, Perekatt, Ansu O., Bie, Wenjun, Gierut, Jessica J., Tyner, Angela L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2767275/
https://ncbi.nlm.nih.gov/pubmed/19501589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2009.05.054
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