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Protein Tyrosine Kinase 6 Negatively Regulates Growth and Promotes Enterocyte Differentiation in the Small Intestine

Protein tyrosine kinase 6 (PTK6) (also called Brk or Sik) is an intracellular tyrosine kinase that is expressed in breast cancer and normal epithelial linings. In adult mice, PTK6 expression is high in villus epithelial cells of the small intestine. To explore functions of PTK6, we disrupted the mou...

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Bibliografiske detaljer
Main Authors: Haegebarth, Andrea, Bie, Wenjun, Yang, Ruyan, Crawford, Susan E., Vasioukhin, Valeri, Fuchs, Elaine, Tyner, Angela L.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489160/
https://ncbi.nlm.nih.gov/pubmed/16782882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01901-05
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