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Disruption of the Mouse Protein Tyrosine Kinase 6 Gene Prevents STAT3 Activation and Confers Resistance to Azoxymethane
BACKGROUND & AIMS: Protein tyrosine kinase 6 (PTK6) is expressed throughout the gastrointestinal tract and is a negative regulator of proliferation that promotes differentiation and DNA-damage induced apoptosis in the small intestine. PTK6 is not expressed in normal mammary gland, but is induced...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3448944/ https://ncbi.nlm.nih.gov/pubmed/21741923 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2011.06.071 |
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