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Disruption of the Mouse Protein Tyrosine Kinase 6 Gene Prevents STAT3 Activation and Confers Resistance to Azoxymethane

BACKGROUND & AIMS: Protein tyrosine kinase 6 (PTK6) is expressed throughout the gastrointestinal tract and is a negative regulator of proliferation that promotes differentiation and DNA-damage induced apoptosis in the small intestine. PTK6 is not expressed in normal mammary gland, but is induced...

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Detaylı Bibliyografya
Asıl Yazarlar: Gierut, Jessica, Zheng, Yu, Bie, Wenjun, Carroll, Robert E., Ball-Kell, Susan, Haegebarth, Andrea, Tyner, Angela L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448944/
https://ncbi.nlm.nih.gov/pubmed/21741923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2011.06.071
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