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E3 ubiquitin ligase Mule targets β-catenin under conditions of hyperactive Wnt signaling

Wnt signaling, named after the secreted proteins that bind to cell surface receptors to activate the pathway, plays critical roles both in embryonic development and the maintenance of homeostasis in many adult tissues. Two particularly important cellular programs orchestrated by Wnt signaling are pr...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Dominguez-Brauer, Carmen, Khatun, Rahima, Elia, Andrew J., Thu, Kelsie L., Ramachandran, Parameswaran, Baniasadi, Shakiba P., Hao, Zhenyue, Jones, Lisa D., Haight, Jillian, Sheng, Yi, Mak, Tak W.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5320996/
https://ncbi.nlm.nih.gov/pubmed/28137882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1621355114
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