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Cellular and Molecular Requirements for the Selection of in vitro-Generated CD8 T Cells Reveals a Role for Notch()
Differentiation of CD8 single-positive (SP) T-cells is predicated by the ability of lymphocyte progenitors to integrate multiple signaling cues provided by the thymic microenvironment. In the thymus and the OP9-DL1 system for T-cell development, Notch signals are required for progenitors to commit t...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3801448/ https://ncbi.nlm.nih.gov/pubmed/23851691 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300417 |
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