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Chronic virus infection drives CD8 T cell-mediated thymic destruction and impaired negative selection
Chronic infection provokes alterations in inflammatory and suppressive pathways that potentially affect the function and integrity of multiple tissues, impacting both ongoing immune control and restorative immune therapies. Here we demonstrate that chronic lymphocytic choriomeningitis virus infectio...
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| Опубликовано в: : | Proc Natl Acad Sci U S A |
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| Главные авторы: | , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7071912/ https://ncbi.nlm.nih.gov/pubmed/32094187 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1913776117 |
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