Chronic virus infection drives CD8 T cell-mediated thymic destruction and impaired negative selection

Chronic infection provokes alterations in inflammatory and suppressive pathways that potentially affect the function and integrity of multiple tissues, impacting both ongoing immune control and restorative immune therapies. Here we demonstrate that chronic lymphocytic choriomeningitis virus infectio...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Elsaesser, Heidi J., Mohtashami, Mahmood, Osokine, Ivan, Snell, Laura M., Cunningham, Cameron R., Boukhaled, Giselle M., McGavern, Dorian B., Zúñiga-Pflücker, Juan Carlos, Brooks, David G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2020
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7071912/
https://ncbi.nlm.nih.gov/pubmed/32094187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1913776117
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