Загрузка...

Chronic virus infection drives CD8 T cell-mediated thymic destruction and impaired negative selection

Chronic infection provokes alterations in inflammatory and suppressive pathways that potentially affect the function and integrity of multiple tissues, impacting both ongoing immune control and restorative immune therapies. Here we demonstrate that chronic lymphocytic choriomeningitis virus infectio...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Elsaesser, Heidi J., Mohtashami, Mahmood, Osokine, Ivan, Snell, Laura M., Cunningham, Cameron R., Boukhaled, Giselle M., McGavern, Dorian B., Zúñiga-Pflücker, Juan Carlos, Brooks, David G.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7071912/
https://ncbi.nlm.nih.gov/pubmed/32094187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1913776117
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!