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IL-10 blockade facilitates DNA vaccine-induced T cell responses and enhances clearance of persistent virus infection

Therapeutic vaccination is a potentially powerful strategy to establish immune control and eradicate persistent viral infections. Large and multifunctional antiviral T cell responses are associated with control of viral persistence; however, for reasons that were mostly unclear, current therapeutic...

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Detalhes bibliográficos
Main Authors: Brooks, David G., Lee, Andrew M., Elsaesser, Heidi, McGavern, Dorian B., Oldstone, Michael B.A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275377/
https://ncbi.nlm.nih.gov/pubmed/18332180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20071948
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