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Therapeutic Blockade of Transforming Growth Factor Beta Fails To Promote Clearance of a Persistent Viral Infection

Persistent viral infections often overburden the immune system and are a major cause of disease in humans. During many persistent infections, antiviral T cells are maintained in a state of immune exhaustion characterized by diminished effector and helper functions. In mammalian systems, an extensive...

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書誌詳細
主要な著者: Garidou, Lucile, Heydari, Sara, Gossa, Selamawit, McGavern, Dorian B.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3416327/
https://ncbi.nlm.nih.gov/pubmed/22553324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00164-12
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