Intrinsic Functional Dysregulation of CD4 T Cells Occurs Rapidly following Persistent Viral Infection

Effective T-cell responses are critical to eradicate acute viral infections and prevent viral persistence. Emerging evidence indicates that robust, early CD4 T-cell responses are important in effectively sustaining CD8 T-cell activity. Herein, we illustrate that virus-specific CD4 T cells are functi...

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Bibliographische Detailangaben
Hauptverfasser: Brooks, David G., Teyton, Luc, Oldstone, Michael B. A., McGavern, Dorian B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2005
Schlagworte:
Pathogenesis and Immunity
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1182641/
https://ncbi.nlm.nih.gov/pubmed/16051844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.16.10514-10527.2005
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