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Reprogramming of antiviral T cells prevents inactivation and restores T cell activity during persistent viral infection

Failure to clear persistent viral infections results from the early loss of T cell activity. A pertinent question is whether the immune response is programmed to fail or if nonresponsive T cells can specifically be fixed to eliminate infection. Although evidence indicates that T cell expansion is pe...

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Autors principals: Brooks, David G., McGavern, Dorian B., Oldstone, Michael B.A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1462941/
https://ncbi.nlm.nih.gov/pubmed/16710479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI26856
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