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Viral persistence redirects CD4 T cell differentiation toward T follicular helper cells

CD4 T cell responses are crucial to prevent and control viral infection; however, virus-specific CD4 T cell activity is considered to be rapidly lost during many persistent viral infections. This is largely caused by the fact that during viral persistence CD4 T cells do not produce the classical Th1...

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Detalhes bibliográficos
Main Authors: Fahey, Laura M., Wilson, Elizabeth B., Elsaesser, Heidi, Fistonich, Chris D., McGavern, Dorian B., Brooks, David G.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3092345/
https://ncbi.nlm.nih.gov/pubmed/21536743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20101773
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