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T-cell receptor β-selection is required at the CD4(+)CD8(+) stage of human T-cell development
T-cell development is predicated on the successful rearrangement of the T-cell receptor (TCR) gene loci, which encode for antigen-specific receptors. Recombination Activating Gene (RAG) 2 is required for TCR gene rearrangements, which occur during specific stages of T-cell development. Here, we diff...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8274368/ https://ncbi.nlm.nih.gov/pubmed/33941655 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.2100141 |
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