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CD8 is required during positive selection of CD4-/CD8+ T cells
Interactions between self-MHC molecules and T cells are necessary for the proper development of mature T cells, in part due to an absolute requirement for self-MHC-TCR interactions. Recently, we showed that CD4- mediated interactions also participate in shaping the T cell repertoire during thymic ma...
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| Natura: | Artigo |
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| Lingua: | Inglês |
| Pubblicazione: |
The Rockefeller University Press
1990
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2187717/ https://ncbi.nlm.nih.gov/pubmed/1968084 |
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