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Human CD8 T cells generated in vitro from hematopoietic stem cells are functionally mature
BACKGROUND: T cell development occurs within the highly specialized thymus. Cytotoxic CD8 T cells are critical in adaptive immunity by targeting virally infected or tumor cells. In this study, we addressed whether functional CD8 T cells can be generated fully in vitro using human umbilical cord bloo...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3072939/ https://ncbi.nlm.nih.gov/pubmed/21429219 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2172-12-22 |
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