Human CD8 T cells generated in vitro from hematopoietic stem cells are functionally mature

BACKGROUND: T cell development occurs within the highly specialized thymus. Cytotoxic CD8 T cells are critical in adaptive immunity by targeting virally infected or tumor cells. In this study, we addressed whether functional CD8 T cells can be generated fully in vitro using human umbilical cord bloo...

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Hlavní autoři: Awong, Génève, Herer, Elaine, La Motte-Mohs, Ross N, Zúñiga-Pflücker, Juan Carlos
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2011
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3072939/
https://ncbi.nlm.nih.gov/pubmed/21429219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2172-12-22
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