Cellular FLICE-inhibitory protein is required for T cell survival and cycling

Fas-associated death domain (FADD) and caspase-8 are key signal transducers for death receptor–induced apoptosis, whereas cellular FLICE-inhibitory protein (cFLIP) antagonizes this process. Interestingly, FADD and caspase-8 also play a role in T cell development and T cell receptor (TCR)–mediated pr...

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Detalhes bibliográficos
Main Authors: Chau, Hien, Wong, Veronica, Chen, Nien-Jung, Huang, Huey-Lan, Lin, Wen-Jye, Mirtsos, Christine, Elford, Alisha R., Bonnard, Madeleine, Wakeham, Andrew, You-Ten, Annick Itie, Lemmers, Bénédicte, Salmena, Leonardo, Pellegrini, Marc, Hakem, Razq, Mak, Tak W., Ohashi, Pamela, Yeh, Wen-Chen
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2005
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213079/
https://ncbi.nlm.nih.gov/pubmed/16043518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20050118
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