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Deficiency of T2K leads to apoptotic liver degeneration and impaired NF-κB-dependent gene transcription
Induction of NF-κB-dependent transcription requires phosphorylation and subsequent degradation of I-κB, an inhibitor of NF-κB, followed by nuclear translocation and DNA binding of NF-κB. Tumor necrosis factor receptor-associated factor 2 (TRAF2) plays a role in NF-κB activation in response to cytoki...
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| Главные авторы: | , , , , , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2000
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC314216/ https://ncbi.nlm.nih.gov/pubmed/10990461 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.18.4976 |
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