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Severe liver degeneration and lack of NF-κB activation in NEMO/IKKγ-deficient mice

Phosphorylation of IκB, an inhibitor of NF-κB, is an important step in the activation of the transcription factor NF-κB. Phosphorylation is mediated by the IκB kinase (IKK) complex, known to contain two catalytic subunits: IKKα and IKKβ. A novel, noncatalytic component of this kinase complex called...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Rudolph, Dorothea, Yeh, Wen-Chen, Wakeham, Andrew, Rudolph, Bettina, Nallainathan, Dhani, Potter, Julia, Elia, Andrew J., Mak, Tak W.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cold Spring Harbor Laboratory Press 2000
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC316493/
https://ncbi.nlm.nih.gov/pubmed/10766741
Tagiau: Ychwanegu Tag
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