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Severe liver degeneration and lack of NF-κB activation in NEMO/IKKγ-deficient mice
Phosphorylation of IκB, an inhibitor of NF-κB, is an important step in the activation of the transcription factor NF-κB. Phosphorylation is mediated by the IκB kinase (IKK) complex, known to contain two catalytic subunits: IKKα and IKKβ. A novel, noncatalytic component of this kinase complex called...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Cold Spring Harbor Laboratory Press
2000
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC316493/ https://ncbi.nlm.nih.gov/pubmed/10766741 |
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