Severe liver degeneration and lack of NF-κB activation in NEMO/IKKγ-deficient mice
Phosphorylation of IκB, an inhibitor of NF-κB, is an important step in the activation of the transcription factor NF-κB. Phosphorylation is mediated by the IκB kinase (IKK) complex, known to contain two catalytic subunits: IKKα and IKKβ. A novel, noncatalytic component of this kinase complex called...
Gespeichert in:
| Veröffentlicht in: | Genes Dev |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cold Spring Harbor Laboratory Press
2000
|
| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316493/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10766741/ |
| Tags: |
Keine Tags, Fügen Sie das erste Tag hinzu!
|