Severe liver degeneration and lack of NF-κB activation in NEMO/IKKγ-deficient mice
Phosphorylation of IκB, an inhibitor of NF-κB, is an important step in the activation of the transcription factor NF-κB. Phosphorylation is mediated by the IκB kinase (IKK) complex, known to contain two catalytic subunits: IKKα and IKKβ. A novel, noncatalytic component of this kinase complex called...
Shranjeno v:
| izdano v: | Genes Dev |
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| Principais autores: | , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Cold Spring Harbor Laboratory Press
2000
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316493/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10766741/ |
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