Viral mediated redirection of NEMO/IKKγ to autophagosomes curtails the inflammatory cascade.

The early host response to viral infections involves transient activation of pattern recognition receptors leading to an induction of inflammatory cytokines such as interleukin-1β (IL-1β) and tumor necrosis factor α (TNFα). Subsequent activation of cytokine receptors in an autocrine and paracrine ma...

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Detalhes bibliográficos

Principais autores:	Patricia M Fliss, Tali Pechenick Jowers, Melanie M Brinkmann, Barbara Holstermann, Claudia Mack, Paul Dickinson, Heinrich Hohenberg, Peter Ghazal, Wolfram Brune
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2012-02-01
coleção:	PLoS Pathogens
Acesso em linha:	http://europepmc.org/articles/PMC3271075?pdf=render
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