Severe liver degeneration and lack of NF-κB activation in NEMO/IKKγ-deficient mice

Phosphorylation of IκB, an inhibitor of NF-κB, is an important step in the activation of the transcription factor NF-κB. Phosphorylation is mediated by the IκB kinase (IKK) complex, known to contain two catalytic subunits: IKKα and IKKβ. A novel, noncatalytic component of this kinase complex called...

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Detalles Bibliográficos

Publicado en:	Genes Dev
Principais autores:	Rudolph, Dorothea, Yeh, Wen-Chen, Wakeham, Andrew, Rudolph, Bettina, Nallainathan, Dhani, Potter, Julia, Elia, Andrew J., Mak, Tak W.
Formato:	Artigo
Idioma:	Inglês
Publicado:	Cold Spring Harbor Laboratory Press 2000
Assuntos:	Research Paper
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316493/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10766741/
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