Activation of antigen-exposed iMC-DCs at the “right place” and “right time” promotes potent anti-tumor immunity

Por Spencer, David M.
Publicado em 2012

MyD88/CD40-based inducible co-stimulation to improve CAR T cell therapy

Por Mata, Melinda, Gerken, Claudia, Spencer, David M, Gottschalk, Stephen
Publicado no J Immunother Cancer (2015)

Synthetic activation of caspases: Artificial death switches

Por MacCorkle, Rebecca A., Freeman, Kevin W., Spencer, David M.
Publicado em 1998

Emerging Vaccine Therapy Approaches for Prostate Cancer

Por Sonpavde, Guru, Slawin, Kevin M, Spencer, David M, Levitt, Jonathan M
Publicado em 2010

A proliferation switch for genetically modified cells

Por Blau, C. Anthony, Peterson, Kenneth R., Drachman, Jonathan G., Spencer, David M.
Publicado em 1997

Caspase-10 is an initiator caspase in death receptor signaling

Por Wang, Jin, Chun, Hyung J., Wong, Wilson, Spencer, David M., Lenardo, Michael J.
Publicado em 2001

Pleiotropic biological activities of alternatively spliced TMPRSS2/ERG fusion gene transcripts

Por Wang, Jianghua, Cai, Yi, Yu, Wendong, Ren, Chengxi, Spencer, David M., Ittmann, Michael
Publicado em 2008

Wnt and Notch Pathways Have Interrelated Opposing Roles on Prostate Progenitor Cell Proliferation and Differentiation

Por Shahi, Payam, Seethammagari, Mamatha R., Valdez, Joseph M., Xin, Li, Spencer, David M.
Publicado em 2011

MyD88/CD40 Genetic Adjuvant Function in Cutaneous Atypical Antigen-Presenting Cells Contributes to DNA Vaccine Immunogenicity

Por Collinson-Pautz, Matthew R., Slawin, Kevin M., Levitt, Jonathan M., Spencer, David M.
Publicado no PLoS One (2016)

A composite MyD88/CD40 switch synergistically activates mouse and human dendritic cells for enhanced antitumor efficacy

Por Narayanan, Priyadharshini, Lapteva, Natalia, Seethammagari, Mamatha, Levitt, Jonathan M., Slawin, Kevin M., Spencer, David M.
Publicado em 2011

Inducible dimerization of FGFR1: development of a mouse model to analyze progressive transformation of the mammary gland

Por Welm, Bryan E., Freeman, Kevin W., Chen, Mercy, Contreras, Alejandro, Spencer, David M., Rosen, Jeffrey M.
Publicado em 2002

Tobacco Mosaic Virus Efficiently Targets DC uptake, Activation and Antigen-specific T Cell Responses in vivo

Por Kemnade, Jan Ole, Seethammagari, Mamatha, Collinson-Pautz, Mathew, Kaur, Hardeep, Spencer, David M., McCormick, Alison
Publicado no Vaccine (2014)

Off-the-shelf Adenoviral-mediated Immunotherapy via Bicistronic Expression of Tumor Antigen and iMyD88/CD40 Adjuvant

Por Kemnade, Jan Ole, Seethammagari, Mamatha, Narayanan, Priya, Levitt, Jonathan M, McCormick, Alison A, Spencer, David M
Publicado em 2012

Double-Inducible Gene Activation System for Caspase 3 and 9 in Epidermis

Por Shah, Viraj R., Koster, Maranke I., Roop, Dennis R., Spencer, David M., Wei, Lei, Li, Qi, Schwartz, Robert J., Chang, Jiang
Publicado em 2007

T Cells Expressing Constitutively Active Akt Resist Multiple Tumor-associated Inhibitory Mechanisms

Por Sun, Jiali, Dotti, Gianpietro, Huye, Leslie E, Foster, Aaron E, Savoldo, Barbara, Gramatges, Maria M, Spencer, David M, Rooney, Cliona M
Publicado em 2010

Intravital imaging of fluorescent markers and FRET probes by DNA tattooing

Por Bins, Adriaan D, van Rheenen, Jacco, Jalink, Kees, Halstead, Jonathan R, Divecha, Nullin, Spencer, David M, Haanen, John BAG, Schumacher, Ton NM
Publicado em 2007

The E3 ligase c-Cbl regulates dendritic cell activation

Por Chiou, Shin-Heng, Shahi, Payam, Wagner, Ryan T, Hu, Hongbo, Lapteva, Natalia, Seethammagari, Mamatha, Sun, Shao-Cong, Levitt, Jonathan M, Spencer, David M
Publicado em 2011

Exposure to sequestered self-antigens in vivo is not sufficient for the induction of autoimmune diabetes

Por Ono, Nobuyuki, Murakami, Kiichi, Chan, Olivia, Hall, Håkan, Elford, Alisha R., Yen, Patty, Calzascia, Thomas, Spencer, David M., Ohashi, Pamela S., Dhanji, Salim
Publicado no PLoS One (2017)

Development of an inducible caspase-9 safety switch for pluripotent stem cell–based therapies

Por Wu, Chuanfeng, Hong, So Gun, Winkler, Thomas, Spencer, David M, Jares, Alexander, Ichwan, Brian, Nicolae, Alina, Guo, Vicky, Larochelle, Andre, Dunbar, Cynthia E
Publicado no Mol Ther Methods Clin Dev (2014)

Level of Endothelial Cell Apoptosis Required for a Significant Decrease in Microvessel Density

Por Dong, Zhihong, Zeitlin, Benjamin D., Song, Wenying, Sun, Qinghua, Karl, Elisabeta, Spencer, David M., Jain, Harsh V., Jackson, Trachette, Núñez, Gabriel, Nör, Jacques E.
Publicado em 2007