Next Generation CAR T Cells for the Immunotherapy of High-Grade Glioma

av Petersen, Christopher T., Krenciute, Giedre
I publikationen Front Oncol (2019)

Hypoxia-inducible CAR expression: An answer to the on-target/off-tumor dilemma?

av Prinzing, Brooke, Krenciute, Giedre
I publikationen Cell Rep Med (2021)

CAR T-cell therapy for glioblastoma: ready for the next round of clinical testing?

av Prinzing, Brooke L., Gottschalk, Stephen M., Krenciute, Giedre
I publikationen Expert Rev Anticancer Ther (2018)

IMMU-20. SELECTING AN EPHA2-CAR FOR THE IMMUNOTHERAPY OF DIPG AND GBM

av Prinzing, Brooke, Yi, Zhongzhen, Chow, Kevin, Gottschalk, Stephen, Krenciute, Giedre
I publikationen Neuro Oncol (2017)

CRISPR-Mediated Non-Viral Site-Specific Gene Integration and Expression in T Cells: Protocol and Application for T-Cell Therapy

av Odé, Zelda, Condori, Jose, Peterson, Nicolas, Zhou, Sheng, Krenciute, Giedre
I publikationen Cancers (Basel) (2020)

Optimizing EphA2-CAR T Cells for the Adoptive Immunotherapy of Glioma

av Yi, Zhongzhen, Prinzing, Brooke L., Cao, Felicia, Gottschalk, Stephen, Krenciute, Giedre
I publikationen Mol Ther Methods Clin Dev (2018)

IMMU-05. B7-H3-SPECIFIC CAR T CELLS HAVE POTENT ANTI-TUMOR ACTIVITY IN THE GL261 IMMUNE-COMPETENT MURINE BRAIN TUMOR MODEL

av Haydar, Dalia, Yi, Zhongzhen, DeRenzo, Chris, Gottschalk, Stephen, Krenciute, Giedre
I publikationen Neuro Oncol (2020)

IM-02 A scFv-BASED CAR TO REDIRECT T CELLS TO IL13Rα2-POSITIVE PEDIATRIC GLIOMA

av Krenciute, Giedre, Krebs, Simone, Torres, David, Lesniak, Maciej, Balyasnikova, Irina, Gottschalk, Stephen
I publikationen Neuro Oncol (2015)

IMMU-14. IMPLICATIONS FOR T-CELL IMMUNOTHERAPY: CELL SURFACE ANTIGEN AND HLA class I EXPRESSION IN PEDIATRIC BRAIN TUMORS ARE HETEROGENOUS

av Houke, Haley, Baker, Suzanne J, Roussel, Martine F, Gottschalk, Stephen, Krenciute, Giedre
I publikationen Neuro Oncol (2019)

IMMU-13. CRISPR/CAS9-MEDIATED SILENCING OF SHP-1 SIGNIFICANTLY ENHANCES THE ANTI-GLIOMA ACTIVITY OF IL-13Rα2 CAR T CELLS

av Petersen, Christopher, Bell, Matthew, Houke, Haley, Yi, Zongzhen, Gottschalk, Stephen, Krenciute, Giedre
I publikationen Neuro Oncol (2019)

Chimeric antigen receptor T-cell therapy in glioblastoma: charging the T cells to fight

av Land, Craig A., Musich, Phillip R., Haydar, Dalia, Krenciute, Giedre, Xie, Qian
I publikationen J Transl Med (2020)

MyD88/CD40 signaling retains CAR T cells in a less differentiated state

av Prinzing, Brooke, Schreiner, Patrick, Bell, Matthew, Fan, Yiping, Krenciute, Giedre, Gottschalk, Stephen
I publikationen JCI Insight (2020)

Inducible Activation of MyD88 and CD40 in CAR T Cells Results in Controllable and Potent Antitumor Activity in Preclinical Solid Tumor Models

av Mata, Melinda, Gerken, Claudia, Nguyen, Phuong, Krenciute, Giedre, Spencer, David M., Gottschalk, Stephen
I publikationen Cancer Discov (2017)

IMMU-17. TRANSGENIC EXPRESSION OF IL15 IMPROVES ANTIGLIOMA ACTIVITY OF IL13RΑ2-CAR T CELLS

av Steffin, David, Prinzing, Brooke, Yi, Zhongzhen, Balyasnikova, Irina, Dotti, Gianpietro, Gottschalk, Stephen, Krenciute, Giedre
I publikationen Neuro Oncol (2017)

Charachterization and functional analysis of scFv-based CARs to redirect T cells to IL13Rα2-positive glioma

av Krenciute, Giedre, Krebs, Simone, Torres, David, Dotti, Gianpietro, Lesniak, Maciej S, Balyasnikova, Irina V, Gottschalk, Stephen
I publikationen J Immunother Cancer (2015)

What is the Optimal Design-Build-Test Cycle for Clinically Relevant Synthetic CAR T Cell Therapies?

av Chen, Yvonne Y., Lim, Wendell, Levings, Megan, Blazar, Bruce, Krenciute, Giedre, Wong, Wilson, Lehner, Manfred
I publikationen Cell Syst (2020)

EXTH-32. TRANSGENIC EXPRESSION OF IL15 IMPROVES THE EFFICACY OF CAR T CELLS IN AN IMMUNE COMPETENT GLIOBLASTOMA MODEL

av Pituch, Katarzyna, Zannikou, Markella, Ilut, Liliana, Chen, Christopher, Lesniak, Maciej, Gottschalk, Stephen, Krenciute, Giedre, Balyasnikova, Irina
I publikationen Neuro Oncol (2018)

EXTH-20. SYNGENEIC B7-H3-SPECIFIC CAR T-CELLS HAVE POTENT ANTI-BRAIN TUMOR ACTIVITY VIA LOCAL OR SYSTEMIC DELIVERY

av Haydar, Dalia, Yi, Zhongzhen, Houke, Haley, Roussel, Martine F, DeRenzo, Chris, Gottschalk, Stephen, Krenciute, Giedre
I publikationen Neuro Oncol (2020)

Transgenic Expression of IL15 Improves Antiglioma Activity of IL13Rα2-CAR T Cells but Results in Antigen Loss Variants

av Krenciute, Giedre, Prinzing, Brooke L., Yi, Zhongzhen, Wu, Meng-Fen, Liu, Hao, Dotti, Gianpietro, Balyasnikova, Irina V., Gottschalk, Stephen
I publikationen Cancer Immunol Res (2017)

Reversible Transgene Expression Reduces Fratricide and Permits 4-1BB Costimulation of CAR T Cells Directed to T-cell Malignancies

av Mamonkin, Maksim, Mukherjee, Malini, Srinivasan, Madhuwanti, Sharma, Sandhya, Gomes-Silva, Diogo, Mo, Feiyan, Krenciute, Giedre, Orange, Jordan S., Brenner, Malcolm K.
I publikationen Cancer Immunol Res (2017)