IMMU-20. SELECTING AN EPHA2-CAR FOR THE IMMUNOTHERAPY OF DIPG AND GBM

The intent of this project is to develop T cells expressing an EphA2-specific chimeric antigen receptor (CAR) as an immunotherapy for diffuse intrinsic pontine glioma (DIPG) and glioblastoma (GBM). EphA2 is an attractive target given its high expression in GBM but not normal brain tissue. We previou...

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Bibliografske podrobnosti
izdano v:Neuro Oncol
Main Authors: Prinzing, Brooke, Yi, Zhongzhen, Chow, Kevin, Gottschalk, Stephen, Krenciute, Giedre
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2017
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Abstracts
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5475122/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.130
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