IMMU-20. SELECTING AN EPHA2-CAR FOR THE IMMUNOTHERAPY OF DIPG AND GBM

The intent of this project is to develop T cells expressing an EphA2-specific chimeric antigen receptor (CAR) as an immunotherapy for diffuse intrinsic pontine glioma (DIPG) and glioblastoma (GBM). EphA2 is an attractive target given its high expression in GBM but not normal brain tissue. We previou...

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Bibliografiske detaljer
Udgivet i:Neuro Oncol
Main Authors: Prinzing, Brooke, Yi, Zhongzhen, Chow, Kevin, Gottschalk, Stephen, Krenciute, Giedre
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2017
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Abstracts
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5475122/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.130
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