PKCθ Signals Activation versus Tolerance In Vivo

Understanding the pathways that signal T cell tolerance versus activation is key to regulating immunity. Previous studies have linked CD28 and protein kinase C-θ (PKCθ) as a potential signaling pathway that influences T cell activation. Therefore, we have compared the responses of T cells deficient...

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Autori principali: Berg-Brown, Nancy N., Gronski, Matthew A., Jones, Russell G., Elford, Alisha R., Deenick, Elissa K., Odermatt, Bernhard, Littman, Dan R., Ohashi, Pamela S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2004
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212730/
https://ncbi.nlm.nih.gov/pubmed/15024044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20031022
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