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Intervention of PKC-θ as an immunosuppressive regimen

PKC-θ is selectively enriched in T cells and specifically translocates to immunological synapse where it mediates critical T cell receptor signals required for T cell activation, differentiation, and survival. T cells deficient in PKC-θ are defective in their ability to differentiate into inflammato...

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Détails bibliographiques
Auteur principal: Sun, Zuoming
Format: Artigo
Langue:Inglês
Publié: Frontiers Research Foundation 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3410430/
https://ncbi.nlm.nih.gov/pubmed/22876242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2012.00225
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