טוען...

Differential requirement of PKC-θ in the development and function of Natural Regulatory T cells

CD4+CD25+ natural Treg cells, which are developed in the thymus, migrate to the periphery to actively maintain self-tolerance. Similar to conventional T cells, TCR signals are critical for the development and activation of Treg cell inhibitory function. While PKC-θ-mediated TCR signals are required...

תיאור מלא

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מידע ביבליוגרפי
Main Authors: Gupta, Sonal, Manicassamy, Santhakumar, Vasu, Chenthamarakshan, Kumar, Anvita, Shang, Weirong, Sun, Zuoming
פורמט: Artigo
שפה:Inglês
יצא לאור: 2008
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2700121/
https://ncbi.nlm.nih.gov/pubmed/18842300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2008.08.275
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