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PKC-θ promotes Th17 differentiation via up-regulation of Stat3
Although protein kinase C-θ (PKC-θ)-deficient mice are resistant to the induction of Th17-dependent experimental autoimmune encephalomyelitis, the function of PKC-θ in Th17 differentiation remains unknown. Here we show that purified, naive CD4 PKC-θ(−/−) T cells were defective in Th17 differentiatio...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3484892/ https://ncbi.nlm.nih.gov/pubmed/22586032 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102941 |
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