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Lipocalin 2-deficient mice exhibit increased sensitivity to Escherichia coli infection but not to ischemia-reperfusion injury

Diverse functions have been reported for lipocalin 2. To investigate these functions in vivo, we generated gene-targeted lipocalin 2-deficient mice (Lcn2(−/−) mice). In vitro studies have suggested that lipocalin 2 is important for cellular apoptosis induced by IL-3 withdrawal, and for the induction...

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Autors principals: Berger, Thorsten, Togawa, Atsushi, Duncan, Gordon S., Elia, Andrew J., You-Ten, Annick, Wakeham, Andrew, Fong, Hannah E. H., Cheung, Carol C., Mak, Tak W.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1413671/
https://ncbi.nlm.nih.gov/pubmed/16446425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0510847103
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