Mnk2 and Mnk1 Are Essential for Constitutive and Inducible Phosphorylation of Eukaryotic Initiation Factor 4E but Not for Cell Growth or Development

Por Ueda, Takeshi, Watanabe-Fukunaga, Rie, Fukuyama, Hidehiro, Nagata, Shigekazu, Fukunaga, Rikiro
Publicado em 2004

Roles of mitogen-activated protein kinase signal-integrating kinases 1 and 2 in oxidant-mediated eIF4E phosphorylation.

Por Shenberger, Jeffrey S., Zhang, Lianqin, Hughlock, Mariah K., Ueda, Takeshi, Watanabe-Fukunaga, Rie, Fukunaga, Rikiro
Publicado em 2007

MNK KINASES FACILITATE C-MYC IRES ACTIVITY IN RAPAMYCIN-TREATED MULTIPLE MYELOMA CELLS

Por Shi, Yijiang, Frost, Patrick, Hoang, Bao, Yang, Yonghui, Fukunaga, Rikiro, Gera, Joseph, Lichtenstein, Alan
Publicado em 2012

Protein Phosphatase 2A Negatively Regulates Eukaryotic Initiation Factor 4E Phosphorylation and eIF4F Assembly through Direct Dephosphorylation of Mnk and eIF4E

Por Li, Yikun, Yue, Ping, Deng, Xingming, Ueda, Takeshi, Fukunaga, Rikiro, Khuri, Fadlo R, Sun, Shi-Yong
Publicado em 2010

Combined deficiency for MAP kinase-interacting kinase 1 and 2 (Mnk1 and Mnk2) delays tumor development

Por Ueda, Takeshi, Sasaki, Masato, Elia, Andrew J., Chio, Iok In Christine, Hamada, Koichi, Fukunaga, Rikiro, Mak, Tak W.
Publicado em 2010

Eukaryotic Translation Initiation Factor 4F Architectural Alterations Accompany Translation Initiation Factor Redistribution in Poxvirus-Infected Cells

Por Walsh, Derek, Arias, Carolina, Perez, Cesar, Halladin, David, Escandon, Martin, Ueda, Takeshi, Watanabe-Fukunaga, Rie, Fukunaga, Rikiro, Mohr, Ian
Publicado em 2008

Correction: The E1A-Associated p400 Protein Modulates Cell Fate Decisions by the Regulation of ROS Homeostasis

Por Mattera, Lise, Courilleau, Céline, Legube, Gaëlle, Ueda, Takeshi, Fukunaga, Rikiro, Chevillard-Briet, Martine, Canitrot, Yvan, Escaffit, Fabrice, Trouche, Didier
Publicado em 2010

The E1A-Associated p400 Protein Modulates Cell Fate Decisions by the Regulation of ROS Homeostasis

Por Mattera, Lise, Courilleau, Céline, Legube, Gaëlle, Ueda, Takeshi, Fukunaga, Rikiro, Chevillard-Briet, Martine, Canitrot, Yvan, Escaffit, Fabrice, Trouche, Didier
Publicado em 2010

Characterization of the Human Herpesvirus 6 U69 Gene Product and Identification of Its Nuclear Localization Signal

Por Isegawa, Yuji, Miyamoto, Yoichi, Yasuda, Yoshinari, Semi, Katsunori, Tsujimura, Kenji, Fukunaga, Rikiro, Ohshima, Atsushi, Horiguchi, Yasuhiro, Yoneda, Yoshihiro, Sugimoto, Nakaba
Publicado em 2008

Mnk1 and 2 are dispensable for T-cell development and activation but important for the pathogenesis of experimental autoimmune encephalitis

Por Gorentla, Balachandra K, Krishna, Sruti, Shin, Jinwook, Inoue, Makoto, Shinohara, Mari L., Grayson, Jason M., Fukunaga, Rikiro, Zhong, Xiao-Ping
Publicado em 2012

Regulatory effects of a Mnk2-eIF4E feedback loop during mTORC1 targeting of human medulloblastoma cells

Por Eckerdt, Frank, Beauchamp, Elspeth, Bell, Jonathan, Iqbal, Asneha, Su, Bing, Fukunaga, Rikiro, Lulla, Rishi R., Goldman, Stewart, Platanias, Leonidas C.
Publicado no Oncotarget (2014)

Negative Regulatory Effects of Mnk Kinases in the Generation of Chemotherapy-Induced Antileukemic Responses

Por Altman, Jessica K., Glaser, Heather, Sassano, Antonella, Joshi, Sonali, Ueda, Takeshi, Watanabe-Fukunaga, Rie, Fukunaga, Rikiro, Tallman, Martin S., Platanias, Leonidas C.
Publicado em 2010

Essential Role for Mnk Kinases in Type II Interferon (IFNγ) Signaling and Its Suppressive Effects on Normal Hematopoiesis

Por Joshi, Sonali, Sharma, Bhumika, Kaur, Surinder, Majchrzak, Beata, Ueda, Takeshi, Fukunaga, Rikiro, Verma, Amit K., Fish, Eleanor N., Platanias, Leonidas C.
Publicado em 2011

Inhibition of Mammalian Target of Rapamycin Induces Phosphatidylinositol 3-Kinase-Dependent and Mnk-Mediated Eukaryotic Translation Initiation Factor 4E Phosphorylation

Por Wang, Xuerong, Yue, Ping, Chan, Chi-Bun, Ye, Keqiang, Ueda, Takeshi, Watanabe-Fukunaga, Rie, Fukunaga, Rikiro, Fu, Haian, Khuri, Fadlo R., Sun, Shi-Yong
Publicado em 2007

Regulation of Arsenic Trioxide-induced Cellular Responses by Mnk1 and Mnk2

Por Dolniak, Blazej, Katsoulidis, Efstratios, Carayol, Nathalie, Altman, Jessica K., Redig, Amanda J., Tallman, Martin S., Ueda, Takeshi, Watanabe-Fukunaga, Rie, Fukunaga, Rikiro, Platanias, Leonidas C.
Publicado em 2008

Type I interferon (IFN)-dependent activation of Mnk1 and its role in the generation of growth inhibitory responses

Por Joshi, Sonali, Kaur, Surinder, Redig, Amanda J., Goldsborough, Katy, David, Kevin, Ueda, Takeshi, Watanabe-Fukunaga, Rie, Baker, Darren P., Fish, Eleanor N., Fukunaga, Rikiro, Platanias, Leonidas C.
Publicado em 2009

Dissecting eIF4E action in tumorigenesis

Por Wendel, Hans-Guido, Silva, Ricardo L.A., Malina, Abba, Mills, John R., Zhu, Hong, Ueda, Takeshi, Watanabe-Fukunaga, Rie, Fukunaga, Rikiro, Teruya-Feldstein, Julie, Pelletier, Jerry, Lowe, Scott. W.
Publicado em 2007

Sprouty Proteins Are Negative Regulators of Interferon (IFN) Signaling and IFN-inducible Biological Responses

Por Sharma, Bhumika, Joshi, Sonali, Sassano, Antonella, Majchrzak, Beata, Kaur, Surinder, Aggarwal, Priya, Nabet, Behnam, Bulic, Marinka, Stein, Brady L., McMahon, Brandon, Baker, Darren P., Fukunaga, Rikiro, Altman, Jessica K., Licht, Jonathan D., Fish, Eleanor N., Platanias, Leonidas C.
Publicado em 2012