Regulation of Arsenic Trioxide-induced Cellular Responses by Mnk1 and Mnk2

Arsenic trioxide (As(2)O(3)) is a potent inducer of apoptosis of malignant cells in vitro and in vivo, but the precise mechanisms by which it mediates such effects are not well defined. We provide evidence that As(2)O(3) induces phosphorylation/activation of the MAPK signal-integrating kinases (Mnks...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Dolniak, Blazej, Katsoulidis, Efstratios, Carayol, Nathalie, Altman, Jessica K., Redig, Amanda J., Tallman, Martin S., Ueda, Takeshi, Watanabe-Fukunaga, Rie, Fukunaga, Rikiro, Platanias, Leonidas C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2008
Témata:
Mechanisms of Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2335346/
https://ncbi.nlm.nih.gov/pubmed/18299328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M708816200
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky