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Suppression of Programmed Cell Death 4 (PDCD4) Protein Expression by BCR-ABL-regulated Engagement of the mTOR/p70 S6 Kinase Pathway

There is accumulating evidence that mammalian target of rapamycin (mTOR)-activated pathways play important roles in cell growth and survival of BCR-ABL-transformed cells. We have previously shown that the mTOR/p70 S6 kinase (p70 S6K) pathway is constitutively activated in BCR-ABL transformed cells a...

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Main Authors: Carayol, Nathalie, Katsoulidis, Efstratios, Sassano, Antonella, Altman, Jessica K., Druker, Brian J., Platanias, Leonidas C.
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2417162/
https://ncbi.nlm.nih.gov/pubmed/18223253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M707934200
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