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Mnk1 and 2 are dispensable for T-cell development and activation but important for the pathogenesis of experimental autoimmune encephalitis

T-cell development and activation are usually accompanied by expansion and production of numerous proteins that require active translation. The eukaryotic translation initiation factor 4E (eIF4E) binds to the 5' cap structure of mRNA and is critical for cap-dependent translational initiation. I...

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Detalhes bibliográficos
Main Authors: Gorentla, Balachandra K, Krishna, Sruti, Shin, Jinwook, Inoue, Makoto, Shinohara, Mari L., Grayson, Jason M., Fukunaga, Rikiro, Zhong, Xiao-Ping
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3552100/
https://ncbi.nlm.nih.gov/pubmed/23269249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200026
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