Sprouty Proteins Are Negative Regulators of Interferon (IFN) Signaling and IFN-inducible Biological Responses

Interferons (IFNs) have important antiviral and antineoplastic properties, but the precise mechanisms required for generation of these responses remain to be defined. We provide evidence that during engagement of the Type I IFN receptor (IFNR), there is up-regulation of expression of Sprouty (Spry)...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Sharma, Bhumika, Joshi, Sonali, Sassano, Antonella, Majchrzak, Beata, Kaur, Surinder, Aggarwal, Priya, Nabet, Behnam, Bulic, Marinka, Stein, Brady L., McMahon, Brandon, Baker, Darren P., Fukunaga, Rikiro, Altman, Jessica K., Licht, Jonathan D., Fish, Eleanor N., Platanias, Leonidas C.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2012
נושאים:
Signal Transduction
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516778/
https://ncbi.nlm.nih.gov/pubmed/23074222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.400721
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