Regulatory effects of mTORC2 complexes in type I IFN signaling and in the generation of IFN responses

IFNs transduce signals by binding to cell surface receptors and activating cellular pathways and regulatory networks that control transcription of IFN-stimulated genes (ISGs) and mRNA translation, leading to generation of protein products that mediate biological responses. Previous studies have show...

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Autors principals: Kaur, Surinder, Sassano, Antonella, Majchrzak-Kita, Beata, Baker, Darren P., Su, Bing, Fish, Eleanor N., Platanias, Leonidas C.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2012
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356630/
https://ncbi.nlm.nih.gov/pubmed/22550181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1118122109
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