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Dual Regulatory Roles of the Phosphatidylinositol 3-Kinase In Interferon Signaling

The phosphatidylinositol (PI) 3-kinase is activated by the Type I and II interferon (IFN) receptors, but its precise role in the generation of IFN responses is not well understood. In the present study we used embryonic fibroblasts from mice with targeted disruption of the genes encoding for both th...

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Detalhes bibliográficos
Main Authors: Kaur, Surinder, Sassano, Antonella, Joseph, Ajith M, Majchrzak-Kita, Beata, Eklund, Elizabeth A., Verma, Amit, Brachmann, Saskia M., Fish, Eleanor N., Platanias, Leonidas C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597572/
https://ncbi.nlm.nih.gov/pubmed/18981154
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