Role of Schlafen 2 (SLFN2) in the Generation of Interferon α-induced Growth Inhibitory Responses

The precise STAT-regulated gene targets that inhibit cell growth and generate the antitumor effects of Type I interferons (IFNs) remain unknown. We provide evidence that Type I IFNs regulate expression of Schlafens (SLFNs), a group of genes involved in the control of cell cycle progression and growt...

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Detalhes bibliográficos
Main Authors: Katsoulidis, Efstratios, Carayol, Nathalie, Woodard, Jennifer, Konieczna, Iwona, Majchrzak-Kita, Beata, Jordan, Alison, Sassano, Antonella, Eklund, Elizabeth A., Fish, Eleanor N., Platanias, Leonidas C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Mechanisms of Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757209/
https://ncbi.nlm.nih.gov/pubmed/19592487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.030445
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