Interferon-Dependent Engagement of Eukaryotic Initiation Factor 4B via S6 Kinase (S6K)- and Ribosomal Protein S6K-Mediated Signals

Although the roles of Jak-Stat pathways in type I and II interferon (IFN)-dependent transcriptional regulation are well established, the precise mechanisms of mRNA translation for IFN-sensitive genes remain to be defined. We examined the effects of IFNs on the phosphorylation/activation of eukaryoti...

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Main Authors: Kroczynska, Barbara, Kaur, Surinder, Katsoulidis, Efstratios, Majchrzak-Kita, Beata, Sassano, Antonella, Kozma, Sara C., Fish, Eleanor N., Platanias, Leonidas C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682034/
https://ncbi.nlm.nih.gov/pubmed/19289497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01537-08
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