MNK KINASES FACILITATE C-MYC IRES ACTIVITY IN RAPAMYCIN-TREATED MULTIPLE MYELOMA CELLS

When mTOR inhibitor rapalogs prevent cap-dependent translation of cell cycle proteins like cmyc, continuing tumor cell growth depends on cap-independent translation, which is mediated by internal ribosome entry sites (IRESes) located in the 5′UTR of transcripts. To investigate if rapalog-induced act...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Shi, Yijiang, Frost, Patrick, Hoang, Bao, Yang, Yonghui, Fukunaga, Rikiro, Gera, Joseph, Lichtenstein, Alan
Formato: Artigo
Idioma:Inglês
Publicado: 2012
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401333/
https://ncbi.nlm.nih.gov/pubmed/22370634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.43
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares