Notch pathway molecules are essential for the maintenance, but not the generation, of mammalian neural stem cells

Neural stem cells, which exhibit self-renewal and multipotentiality, are generated in early embryonic brains and maintained throughout the lifespan. The mechanisms of their generation and maintenance are largely unknown. Here, we show that neural stem cells are generated independent of RBP-Jκ, a key...

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Detaylı Bibliyografya
Asıl Yazarlar: Hitoshi, Seiji, Alexson, Tania, Tropepe, Vincent, Donoviel, Dorit, Elia, Andrew J., Nye, Jeffrey S., Conlon, Ronald A., Mak, Tak W., Bernstein, Alan, van der Kooy, Derek
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory Press 2002
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC186324/
https://ncbi.nlm.nih.gov/pubmed/11937492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.975202
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