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Notch pathway molecules are essential for the maintenance, but not the generation, of mammalian neural stem cells
Neural stem cells, which exhibit self-renewal and multipotentiality, are generated in early embryonic brains and maintained throughout the lifespan. The mechanisms of their generation and maintenance are largely unknown. Here, we show that neural stem cells are generated independent of RBP-Jκ, a key...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Cold Spring Harbor Laboratory Press
2002
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC186324/ https://ncbi.nlm.nih.gov/pubmed/11937492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.975202 |
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