WNT/NOTCH Pathway Is Essential for the Maintenance and Expansion of Human MGE Progenitors

Medial ganglionic eminence (MGE)-like cells yielded from human pluripotent stem cells (hPSCs) hold great potentials for cell therapies of related neurological disorders. However, cues that orchestrate the maintenance versus differentiation of human MGE progenitors, and ways for large-scale expansion...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Ma, Lin, Wang, Yiran, Hui, Yi, Du, Yanhua, Chen, Zhenyu, Feng, Hexi, Zhang, Shuwei, Li, Nan, Song, Jianren, Fang, Yujiang, Xu, Xiangjie, Shi, Lei, Zhang, Bowen, Cheng, Jiayi, Zhou, Shanshan, Liu, Ling, Zhang, Xiaoqing
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6524734/
https://ncbi.nlm.nih.gov/pubmed/31056478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2019.04.007
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