Protection of ZIKV infection-induced neuropathy by abrogation of acute antiviral response in human neural progenitors

It remains largely unknown how Zika virus (ZIKV) infection causes severe microcephaly in human newborns. We examined an Asian lineage ZIKV, SZ01, which similarly infected and demonstrated comparable growth arrest and apoptotic pathological changes in human neuroprogenitors (NPCs) from forebrain dors...

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Udgivet i:Cell Death Differ
Main Authors: Liu, Ling, Chen, Zhenyu, Zhang, Xin, Li, Shun, Hui, Yi, Feng, Hexi, Du, Yanhua, Jin, Guohua, Zhou, Xiaohui, Zhang, Xiaoqing
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7224299/
https://ncbi.nlm.nih.gov/pubmed/30952992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-019-0324-7
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