Protection of ZIKV infection-induced neuropathy by abrogation of acute antiviral response in human neural progenitors

It remains largely unknown how Zika virus (ZIKV) infection causes severe microcephaly in human newborns. We examined an Asian lineage ZIKV, SZ01, which similarly infected and demonstrated comparable growth arrest and apoptotic pathological changes in human neuroprogenitors (NPCs) from forebrain dors...

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Pubblicato in:Cell Death Differ
Autori principali: Liu, Ling, Chen, Zhenyu, Zhang, Xin, Li, Shun, Hui, Yi, Feng, Hexi, Du, Yanhua, Jin, Guohua, Zhou, Xiaohui, Zhang, Xiaoqing
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7224299/
https://ncbi.nlm.nih.gov/pubmed/30952992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-019-0324-7
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